Pho91 Is a Vacuolar Phosphate Transporter That Regulates Phosphate and Polyphosphate Metabolism in Saccharomyces cerevisiae
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چکیده
منابع مشابه
A vacuolar phosphate transporter essential for phosphate homeostasis in Arabidopsis.
Inorganic phosphate (Pi) is stored in the vacuole, allowing plants to adapt to variable Pi availability in the soil. The transporters that mediate Pi sequestration into vacuole remain unknown, however. Here we report the functional characterization of Vacuolar Phosphate Transporter 1 (VPT1), an SPX domain protein that transports Pi into the vacuole in Arabidopsis. The vpt1 mutant plants were st...
متن کاملPhysiological regulation of the derepressible phosphate transporter in Saccharomyces cerevisiae.
The extracellular phosphate concentration permissive for the expression of different amounts of the active high-affinity Pho84 phosphate transporter in the plasma membrane as well as the PHO84 messenger RNA levels in low-phosphate-grown Saccharomyces cerevisiae cells is very narrow and essential for a tight regulation of the transporter. The Pho84 transporter undergoes a rapid degradation once ...
متن کاملNew components of a system for phosphate accumulation and polyphosphate metabolism in Saccharomyces cerevisiae revealed by genomic expression analysis.
The PHO regulatory pathway is involved in the acquisition of phosphate (P(i)) in the yeast Saccharomyces cerevisiae. When extracellular P(i) concentrations are low, several genes are transcriptionally induced by this pathway, which includes the Pho4 transcriptional activator, the Pho80-Pho85 cyclin-CDK pair, and the Pho81 CDK inhibitor. In an attempt to identify all the components regulated by ...
متن کاملPhosphate transport and sensing in Saccharomyces cerevisiae.
Cellular metabolism depends on the appropriate concentration of intracellular inorganic phosphate; however, little is known about how phosphate concentrations are sensed. The similarity of Pho84p, a high-affinity phosphate transporter in Saccharomyces cerevisiae, to the glucose sensors Snf3p and Rgt2p has led to the hypothesis that Pho84p is an inorganic phosphate sensor. Furthermore, pho84Delt...
متن کاملCharacterization of Phosphate Membrane Transport in Saccharomyces cerevisiae CEN.PK113-5D under Low-Phosphate Conditions Using Aerobic Continuous Culture
Two different growth media, namely complex and defined media, were used to examine establishment of steady-state conditions in phosphate-limited culture system of Saccharomyces cerevisiae CEN.PK113-5D strain. Using the defined growth medium, it was possible to obtain steady state condition in the continuous culture. The effect of phosphate concentration on the growth of S. cerevisiae in pho...
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ژورنال
عنوان ژورنال: Molecular Biology of the Cell
سال: 2007
ISSN: 1059-1524,1939-4586
DOI: 10.1091/mbc.e07-05-0457